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Total 22897 results found since Jan 2013.
Association between weight loss agents and elevated liver enzymes: a population-based cross-sectional study
This study aimed to investigate the associations between weight loss agents and elevated liver enzymes at the population-level. We conducted a cross-sectional study using Korea National Health and Nutrition Examination Survey (KNHANES) data from 2013 to 2019. This study included 36,259 participants over 20 years of age who completed the questionnaire and had no history of hepatitis, cancer, or renal failure. In these participants, we analyzed associations between weight loss agents and elevated liver enzymes by constructing multiple logistic regression models with adjustment for confounding factors and stratified by sex, a...
Source: Cancer Control - September 22, 2023 Category: Cancer & Oncology Authors: Ye-Jee Kim Seo Young Kang Mi-Sook Kim Joongyub Lee Bo Ram Yang Source Type: research
Catechin hydrate ameliorates cerulein ‑induced chronic pancreatitis via the inactivation of TGF‑β/Smad2 signaling
Mol Med Rep. 2023 Nov;28(5):208. doi: 10.3892/mmr.2023.13095. Epub 2023 Sep 21.ABSTRACTChronic pancreatitis (CP) is a pancreatic inflammatory disease associated with histological changes, including fibrosis, acinar cell loss and immune cell infiltration, and leads to damage of the pancreas, which results in pain, weight loss and loss of pancreas function. Catechin or catechin hydrate (CH) has antioxidant, anticancer and immune‑regulatory effects. However, unlike other catechins, the antifibrotic effects of (+)‑CH have not been widely studied in many diseases, including CP. Therefore, the anti‑fibrotic effects of (+)â...
Source: Molecular Medicine - September 21, 2023 Category: Molecular Biology Authors: Bitna Kweon Dong-Uk Kim Jin-Young Oh Sung-Joo Park Gi-Sang Bae Source Type: research
Modeling and investigation of swelling kinetics of sodium carboxymethyl cellulose/starch/citric acid superabsorbent polymer
Int J Biol Macromol. 2023 Sep 19:127013. doi: 10.1016/j.ijbiomac.2023.127013. Online ahead of print.ABSTRACTCrosslinked hydrophilic polymers with high water absorption rates are known as superabsorbent polymers (SAPs). Most commercial superabsorbent polymers are made with acrylic acid, which is difficult to biodegrade. So, in this investigation, carboxymethyl cellulose (CMC) was utilized as a significant component in the synthesis of polysaccharide-based SAPs. Citric acid (CA) and starch were chosen as crosslinking agents because they are more eco-friendly, non-toxic, and biodegradable than traditional crosslinking agents....
Source: International Journal of Biological Macromolecules - September 21, 2023 Category: Biochemistry Authors: Cheera Prasad Seo Young Park Jai Sung Lee Jae Jun Park Yeonju Jang Sung Woo Lee Byoung-Min Lee You-Ree Nam A Karteek Rao Hyeong Yeol Choi Source Type: research
Enhanced biofuel production by co-pyrolysis of distiller's grains and waste plastics: A quantitative appraisal of kinetic behaviors and product characteristics
In this study, the co-pyrolysis of a common biomass, i.e. distiller's grains (DG), and waste polypropylene plastic (PP) were investigated towards increasing the quantity and quality of the production of biofuel. Results from the thermogravimetric analyses showed that the reaction interval of individual pyrolysis of DG and PP was 124-471 °C and 260-461 °C, respectively. Conversely, an interaction effect between DG and PP was observed during co-pyrolysis, resulting in a slower rate of weight loss, a longer temperature range for the pyrolysis reaction, and an increase in the temperature difference between the evolution of p...
Source: Chemosphere - September 20, 2023 Category: Chemistry Authors: Gang Li Tenglun Yang Wenbo Xiao Xiaolong Yao Meng Su Minmin Pan Xiqing Wang Tao Lyu Source Type: research
Highlighting the idea of exerkines in the management of cancer patients with cachexia: novel insights and a critical review
CONCLUSION: Our understanding of the underlying physiological mechanisms related to the significance of investigating exerkines in cancer cachexia is currently quite basic. Nonetheless, this demonstrated that resistance and aerobic exercise can contribute to the reduction and control of the disease in individuals with cancer cachexia, as well as in survivors, by inducing changes in exerkines.PMID:37730552 | DOI:10.1186/s12885-023-11391-3
Source: Cancer Control - September 20, 2023 Category: Cancer & Oncology Authors: Amirhossein Ahmadi Hekmatikar Andr é Nelson Aaron Petersen Source Type: research
Enhanced biofuel production by co-pyrolysis of distiller's grains and waste plastics: A quantitative appraisal of kinetic behaviors and product characteristics
In this study, the co-pyrolysis of a common biomass, i.e. distiller's grains (DG), and waste polypropylene plastic (PP) were investigated towards increasing the quantity and quality of the production of biofuel. Results from the thermogravimetric analyses showed that the reaction interval of individual pyrolysis of DG and PP was 124-471 °C and 260-461 °C, respectively. Conversely, an interaction effect between DG and PP was observed during co-pyrolysis, resulting in a slower rate of weight loss, a longer temperature range for the pyrolysis reaction, and an increase in the temperature difference between the evolution of p...
Source: Chemosphere - September 20, 2023 Category: Chemistry Authors: Gang Li Tenglun Yang Wenbo Xiao Xiaolong Yao Meng Su Minmin Pan Xiqing Wang Tao Lyu Source Type: research
Polycystic Kidney Disease Diet: What Is Known and What Is Safe
Clin J Am Soc Nephrol. 2023 Sep 20. doi: 10.2215/CJN.0000000000000326. Online ahead of print.ABSTRACTAutosomal dominant polycystic kidney disease (ADPKD) is a genetic disorder characterized by kidney cyst formation and progressive kidney function loss. Dietary interventions such as caloric restriction, intermittent fasting, and the ketogenic diet have recently emerged as potential strategies to induce metabolic reprogramming and slow ADPKD progression. We review the available evidence supporting the efficacy and safety of these interventions in ADPKD. Dietary interventions show promise in managing ADPKD by improving metabo...
Source: Clinical Journal of the American Society of Nephrology : CJASN - September 20, 2023 Category: Urology & Nephrology Authors: Fouad T Chebib Kristen L Nowak Michel B Chonchol Kristen Bing Ahmad Ghanem Frederic F Rahbari-Oskoui Neera K Dahl Michal Mrug Source Type: research
Endoscopic therapies for patients with obesity: a systematic review and meta-analysis
ConclusionThis review is the first to evaluate various endoscopic bariatric therapies using only RCTs and observational studies for evaluation of weight loss compared with conservative management, lifestyle modification, and  bariatric surgery. Endoscopic therapies result in greater weight loss compared to lifestyle modification, but not as much as bariatric surgery. Endoscopic therapies may be beneficial as an alternative to bariatric surgery.
Source: Surgical Endoscopy - September 20, 2023 Category: Surgery Source Type: research
Feasibility and acceptability of miracle fruit application prior to the consumption of sour-tasting foods as a weight-loss strategy in adults with diabetes or prediabetes: A randomized crossover trial
Appetite. 2023 Sep 17:107046. doi: 10.1016/j.appet.2023.107046. Online ahead of print.ABSTRACTMiracle fruit (MF) has emerged as a promising option for healthy noncaloric sweeteners due to its sour-to-sweet taste-modifying effects and high antioxidant activity. We aimed to examine the feasibility and acceptability of using MF as a weight-loss strategy for individuals with diabetes or prediabetes. Fifty Korean-American men and women (25 participants each) aged 45-75 years with diabetes or prediabetes were recruited in this study. They participated in a randomized placebo-controlled crossover trial where they took the assigne...
Source: Appetite - September 19, 2023 Category: Nutrition Authors: Sung Eun Choi Taehwan Park Source Type: research
Osteopontin-driven T-cell accumulation and function in adipose tissue and liver promoted insulin resistance and MAFLD
CONCLUSIONS: Current findings highlight a critical role of SPP1 in the initiation of obesity-driven chronic inflammation by regulating accumulation and/or polarization of T cells. Early targeting of SPP1 could be beneficial for IR and MAFLD treatment.PMID:37724058 | DOI:10.1002/oby.23868
Source: Obesity - September 19, 2023 Category: Eating Disorders & Weight Management Authors: Fr édéric Soysouvanh D éborah Rousseau St éphanie Bonnafous Manon Bourinet Axelle Strazzulla St éphanie Patouraux Jean Machowiak Marwin A Farrugia Antonio Iannelli Albert Tran Rodolphe Anty Carmelo Luci Philippe Gual Source Type: research
Feasibility and acceptability of miracle fruit application prior to the consumption of sour-tasting foods as a weight-loss strategy in adults with diabetes or prediabetes: A randomized crossover trial
Appetite. 2023 Sep 17:107046. doi: 10.1016/j.appet.2023.107046. Online ahead of print.ABSTRACTMiracle fruit (MF) has emerged as a promising option for healthy noncaloric sweeteners due to its sour-to-sweet taste-modifying effects and high antioxidant activity. We aimed to examine the feasibility and acceptability of using MF as a weight-loss strategy for individuals with diabetes or prediabetes. Fifty Korean-American men and women (25 participants each) aged 45-75 years with diabetes or prediabetes were recruited in this study. They participated in a randomized placebo-controlled crossover trial where they took the assigne...
Source: Appetite - September 19, 2023 Category: Nutrition Authors: Sung Eun Choi Taehwan Park Source Type: research
Absorption of an Engineered Medium Chain Fatty Acid Analogue in Two Short Bowel Syndrome Minipig Models
CONCLUSION: In two SBS-IF minipig models, SEFA-6179 had substantially decreased absorption compared to pre-resection minipigs. Dose optimization for different intestinal anatomy and function may be required. We describe a new SBS-IF pseudojejunostomy model that may improve the translation of preclinical research to SBS-IF patients with enterostomies. This article is protected by copyright. All rights reserved.PMID:37726175 | DOI:10.1002/jpen.2563
Source: JPEN Journal Of Parenteral And Enteral Nutrition - September 19, 2023 Category: Nutrition Authors: Scott C Fligor Savas T Tsikis Thomas I Hirsch Amy Pan Paul D Mitchell Mikayla Quigley Sarah Carbeau Arthur Nedder Kathleen M Gura Mark Puder Source Type: research
Gestational Diabetes Mellitus: Update on Screening, Diagnosis, and Management
Am Fam Physician. 2023 Sep;108(3):249-258.ABSTRACTGestational diabetes mellitus (GDM) is a common condition of pregnancy with increasing prevalence in the United States. GDM increases risks of complications, including operative delivery, hypertensive disorders, shoulder dystocia, fetal macrosomia, large-for-gestational-age infants, neonatal hypoglycemia, and neonatal respiratory distress. In patients who are overweight or obese, prepregnancy weight loss and lifestyle modifications during pregnancy may prevent GDM. First-trimester screening can identify preexisting diabetes and early-onset GDM for prompt implementation of g...
Source: American Family Physician - September 19, 2023 Category: Primary Care Authors: Joshua S Will Holly Crellin Source Type: research
Osteopontin-driven T-cell accumulation and function in adipose tissue and liver promoted insulin resistance and MAFLD
CONCLUSIONS: Current findings highlight a critical role of SPP1 in the initiation of obesity-driven chronic inflammation by regulating accumulation and/or polarization of T cells. Early targeting of SPP1 could be beneficial for IR and MAFLD treatment.PMID:37724058 | DOI:10.1002/oby.23868
Source: Obesity - September 19, 2023 Category: Eating Disorders & Weight Management Authors: Fr édéric Soysouvanh D éborah Rousseau St éphanie Bonnafous Manon Bourinet Axelle Strazzulla St éphanie Patouraux Jean Machowiak Marwin A Farrugia Antonio Iannelli Albert Tran Rodolphe Anty Carmelo Luci Philippe Gual Source Type: research
